ABSTRACT
Myalgia and headache are relatively common in COVID-19 disease, but a serious neurological disease is uncommon. In this case, we describe the symptoms and clinic of AMSAN, a rare variant of Guillain Barre syndrome (GBS) due to COVID 19. We presented a case of AMSAN, a rare variant of GBS, in a 46-year-old male patient with poor overall condition that did not recover after COVID-19 disease, loss of strength and decreased sensation in distal limbs. electromyography-nerve conduction study findings were suggestive acute motor and sensory axonal neuropathy. Cerebrospinal fluid analysis was elevated protein with a normal white blood cell count. The clinical diagnosis of AMSAN supported by results of diagnostic testing such as cerebrospinal fluid and electromyography-nerve conduction study.
ABSTRACT
Introduction: Dialysis patients may have a very high prevalence and death rate for COVID-19. The aim of this study is to show the level of antibody against SARS-CoV-2 in hemodialysis and staff working in the same dialysis center. Methods: Anti-SARS-CoV-2 IgG antibodies were studied in 156 hemodialysis patients and 27 staff. After a 5-minute resting period, blood pressure was measured and then subsequent to an approximately 12-hour fasting period, blood sample were drawn for biochemistry parameters and anti-SARS-CoV-2 IgG antibodies. Results: Three of hemodialysis patients were diagnosed with COVID-19 in March and their PCR tests were positive. The symptoms of these patients were extreme fatigue and muscle weakness. Anti-SARS-CoV-2 IgG antibodies tests were performed on all patients and staff in July. In total, 13/156 ( 8.3%) patients were diagnosed as COVID-19 based on anti-SARS-CoV-2 antibodies. The other 10 patients were asymptomatic. The staff and 143 hemodialysis patients had IgG (-). Hemodialysis patients who had anti-SARS-CoV-2 IgG (+) antibodies had decreased level of haemoglobin and high levels of C-reactive protein and alkaline phosphatase. Conclusions: Antibody tests are particularly important for detecting people with COVID-19 who have few or no symptoms. It has also been seen that the spread of infection in the dialysis center can be prevented by very strict precautions.